Determination of infection potential and genetic structure of microbes from healthcare and municipal wastes in Kathmandu, Nepal.

With the interest and expertise in infectious disease research, we are working on a project determining infection potential and genetic structure of microbes from healthcare and municipal wastes in Kathmandu.

Healthcare waste is defined as all the wastes generated by healthcare facilities, medical laboratories and biomedical research facilities, as well as wastes from minor or scattered sources. Healthcare wastes continue to be a major challenge, particularly in developing world like Nepal due to poor conduct and inappropriate handling and disposal methods. These wastes are regarded as highly infectious or hazardous in nature due to the presence of infectious microbes like bacteria, viruses, fungi and parasites. Though the harms associated with these wastes have gained public concern and discussed in different events, forum and summits, we do not have available data on types and potential infections. We are still lack of characterization of microbes and required steps to reduce occupational incidents and environmental contamination especially, in crowded places like Kathmandu where healthcare centers and public inhabitant are very close by. The improper treatment and disposal of healthcare wastes may result in increasing chances of serious health hazards to public due to exposure to infectious agents. Therefore, we aim to study microbial load and their infection potential, variation in microbial strains and pathogenicity, nature of antibiotics resistance and genetic determinants of microbes in wastes from healthcare and municipal in Kathmandu valley. As a long term goal, these informations will be exploited for mechanistic study of multi drug resistance which is the major concern with any infectious diseases. Therefore, this intended study will not only provide excellent public health concerned scientific data, but also alert general public on waste management and will support the stakeholders to make effective policy in waste management which in turn will help in reducing disease burden substantial.

Project Team:

Deena Shrestha Bajracharya, PhD. (Principal Investigator)

Bivek Timalsina, MSc. (Co-Principal Investigator)

Satya Raj Poudel (Thesis student)


The project is funded by The World Academy of Sciences (TWAS).

Posted In: Projects August 6th, 2017

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