With the interest and expertise in infectious disease research, we are working on a project determining infection potential and genetic structure of microbes from healthcare and municipal wastes in Kathmandu. Healthcare waste is defined as all the wastes generated by healthcare facilities, medical laboratories and biomedical research facilities, as well as wastes from minor or scattered […]

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August 6th, 2017

Non-small cell lung carcinoma (NSLC) is one of the subtypes of lung cancer. Mutation in epidermal growth factor receptor (EGFR) is commonly found in NSLC patients, specifically in lung adenocarcinoma. Therefore, EGFR inhibitors may be used as an effective first line of chemotherapy to treat NSCLC. Two classes of EGFR inhibitor are available: Monoclonal antibodies […]

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August 5th, 2017

Dr. Roshan Lal Shrestha recently contributed a book chapter for INTECT open science publication, titled How are Dynamic Microtubules Stably Tethered to Human Chromosomes? Abstract During cell division, microtubules capture and pull chromosomes apart into two equal sets. Without the establishment of proper chromosome-microtubule attachment, microtubules cannot impart the pulling forces needed to separate sister […]

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August 5th, 2017

Dr. Roshan Lal Shrestha, a scientific team member of CHDS-Nepal, recently published a paper in Oncotarget. This was the work that Dr. Shrestha is doing as a postdoctoral fellow at National Cancer Institute, National Institutes of health, USA. This paper describes desregulation of a protein may contribute to tumor development. Abstract: Chromosomal instability (CIN) is a […]

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August 5th, 2017

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